Hoechst 34580_23555-00-2_DataSheet_MedChemExpress

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Product Name:

Hoechst 34580CAS No.:

23555-00-2Cat. No.:

HY-15560

Product Data Sheet

MWt:

451.57Formula:

C27H29N7Purity :>98%

Solubility:

DMSO or water Protect from light

Mechanisms:

Biological Activity:

Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA Hoechst 34580is a Pathways:Others; Target:DNA Stain Hoechst stains are part of a family of blue fluorescent dyes used to stain DNA. Hoechst 34580 is a

cell dye for DNA.

IC50 Value: These Bis-benzimides were originally developed by Hoechst AG, which numbered all their

compounds so that the dye Hoechst 33342 is the 33342nd compound made by the company. There are three related Hoechst stains: Hoechst 33258, Hoechst 33342, and Hoechst 34580. The dyes Hoechst 33258 and Hoechst 33342 are the ones most commonly used and they have

similarexcitation/emission spectra. Both dyes are excited by ultraviolet light at around 350 nm, and

both emit blue/cyan fluorescent light around anemission maximum at 461 nm. Unbound dye has its

References:

[1]. Portugal J, Waring MJ. Assignment of DNA binding sites for 4',6-diamidine-2-phenylindole and bisbenzimide (Hoechst 33258). A comparative footprinting study. Biochimica et Biophysica Acta 949

(2): 158-68.y g y maximum fluorescence emission in the 510-540 nm range. Hoechst dyes are soluble in water and in organic solvents such as dimethyl formamide or dimethyl sulfoxide. Concentrations can be achieved of up to 10 m...

()

[2]. a b c "Hoechst Stains". Invitrogren (Molecular Probes).[3]. Latt SA, Stetten G, Juergens LA, Recent developments in the detection of deoxyribonucleic acid synthesis by 33258 Hoechst fluorescence. The journal of histochemistry and cytochemistry : official

journal of the Histochemistry Society 23 (7): 493-505.Caution: Not fully tested. For research purposes only

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